Tuesday
   March 9, 2010

Health Alerts
Click for Eastsound, Washington Forecast

| Living Safely On Your Own | Comparisions of Prescription Drug Plans | A Medication Reminder |
| Potentially Inappropriate Drugs for Older Adults | Clostridium difficile, A Dangerous Superbug | Calcium Supplements - How much REALLY? |
| Heart Failure | Hand Washing 101 | How Low Should You Go? |
| Sleep Deprivation | Red Flag For Women | It Could Be A Warning of A Stroke |
| Detecting Delirium | Viagra and Sleep Apnea | Gastroesophageal Reflux Disease (GERD) |
| Distinguishing Normal "Senior Moments" | Sleep and your Blood Pressure | Primer on Cataracts |
| Antidepressant-Induced Sexual Dysfunction |
Reduce Your Fall Risk
Age related changes in the inner ear can affect your hearing and your balance. Impared hearing is one of the most common conditions in older adults. According to the National Institutes of Health (NIH), it affects 75% of those age 85 and older. It can make communication difficult and cause social isolation and depression; but, its effects can also can be more physical, because the inner ear is closely associated with balance - a fact underlined by recent research associating hearing loss with walking difficulties that increase the risk of falls.

It's normal with aging to experience a decline in both hearing and the balance nerve cells located in the inner ear. The latter control balance by providing ongoing feedback via nerve signals to the brain about the head's motion and position relative to gravity. Studies have shown that the reduction in the number of nerve cells in the vestibular system of the inner ear begins at about age 55. There can also be a decline in the nerve cells of the cerebellum - an area of the brain that is involved in balance and posture - and the brain stem, which receive those signals. In spite of any other health factors that may be involved, the study published in theJournal of the American Geriatrics Society does show a correlation between hearing loss and walking difficulties.

Taking steps to preserve your hearing could potentially improve your balance and help you avoid the walking difficulties that could put you at risk of falls. If you are suffering from dizziness or unsteadiness that affects your balance, consult with your doctor who can take steps to ensure that your vestibular system is functioning properly.

UCLA Medical Center, Division of Geriatrics

Living Safely On Your Own
According to the U.S. Census Bureau, more than six million adults age 75 and older lived alone in 2006. For many, the principal reason in doing so is independence; but it isn't always easy if struggling with a chronic illness or some disability. Then too, living alone has its own risks. You can't assume accidents like a fall won't happen to you; but this doesn't mean you shouldn't live by yourself. The answer is preparation.

Preparation is the key to safety when living alone. Start by creating a written and detailed Action Plan that will help protect you, and comfort those who worry about you being by yourself, in the event of an emergency.

These guidelines should be incorporated into your Action Plan:

  • Decide who you will call in an emergency (911 or a friend, neighbor, family member, etc.)Tape these phone numbers to back of every phone in the house and tell the people you've selected that they are on your emergency contact list.
  • Visualize how you are going to get to the telephone.Consider where the phones are and make sure there is a phone in the rooms you frequent the most; especially, the bathroom where many falls take place. Remember, you may have to crawl or slide to a phone.
  • Have daily conversations with friends or family. This will keep you socially engaged and at the same time provide a safety net - if you don't call or answer a call the person you talk to every day will know something may be wrong.
  • Have a document in an accessible place (like on the refrigerator or the bedroom bureau), listing your name SSA number, insurance information, and all other important medical information.
  • Consider getting a personal emergency response system that is worn around the neck or wrist. These allow you to press a button that immediately contacts emergency personnel in case of an accident.
  • Prepare your home. Home modifications will help preserve your independence and your safety. You can install simple solutions yourself - like high-watt-low energy lightbulbs and nonslip pads on stairs, bathroom tiles, and furniture. Ask you doctor to prescribe a home evaluation in order to have a physical or occupational therapist assess your home and decide which medical equipment or renovations would be best for you. Midicare may pay for evaluations and equipment if deemed medically necessary.
If you decide that you need help, visit these web-sites for information regarding home care agenciesin or near your area:
  • Medicare (www.medicare.gov) Scroll down to the bottom left of the home page to find the link "Compare Home Health Agencies In Your Area". Click to find Medicare approved home health agencies near you, along with information on your rights as a home health patient and what to expect when you hire an aide or nurse.
  • Eldercare (www.eldercare.gov/Eldercare.net) This web-site allows you to search by zip code, city, or state to find caretaker resources, along with other helpful news regarding living alone and aging.
  • Independent Living Centers (www.virtualcil.net/cils) to locate organizations in your area that help older people who live alone.
Johns Hopkins Medical Letter

Comparisions of Prescription Drug Plans
You may be interested to know that in San Juan County, Washington there are some 48 Prescription Drug Plans from which you may choose. To see a comprehensive comparison chart go to http://www.medicare.gov

You will be asked to select a State and provide the County name in which you reside. You will then need to click 'Show Plans' and scroll down to the comparison chart. Now you should be better able to make an informed decision as to which plan best suits your needs.



A Medication Reminder
Taking medication as prescribed is an essential part of caring for yourself while you are ill, but a recent study from Emory University found that 20-50% of patients take their medications incorrectly. Reminders, like pill boxes labeled with days of the week can help people keep track of their medications. And now the federal Agency for Healthcare Research and Quality (AHRQ) has created a pill card to give you another way to remember what you need to take and how to take it.

You can find the AHRQ card template on the Internet at ( www.ahrq.gov/qual/pillcard/pillcard.htm) and print it out or save it to your personal computer so you can customize it with your own medication instructions.

To avoid medication mix-ups, the AHRQ recommends that you describe each type of pill - its shape and color, for instance - and note any distinct markings if two pills look alike. To help with this, the AHRQ website contains images of pills that you can copy, color on the computer, and add to your pill card. You can also do this by hand.

Keep your pill card near your medications or in a visible place, like on the refrigerator or bathroom mirror.

Review your pill card with your doctor periodically to make sure that your dosages are correct and that you're not still taking anything that you do not need. Also, check with your pharmacist if you notice a change in the color, shape or size of your pills - generic medicines in particular often change appearance.

The Johns Hopkins Medical Letter

Potentially Inappropriate Drugs for Older Adults
As the years add up, it's not unusual for the number of daily medications we take to increase.Older persons may have trouble tolerating medications better suited for younger patients.

One of the most important steps you can take to protect yourself is to supply all of your doctors, particularly specialists, with as complete a medical status as possible, including a list of conditions you have and the drugs and supplements you take.

The following 33 drugs are considered to be potentially inappropriate for patients 65 years of age and older and may result in various adverse effects:

DRUG(generic/brand name) ADVERSE EFFECTS

  • Barbiturates(Nembutol, Mebarol, Amobarbital, Butabarbital, Pentabarbital, Secobarbital) Highly addictive,more adverse effects than most sedatives
  • Flurazepam(Dalmane, Somnol, Novo-Flupam, Apo-Flurazepam)May cause Central Nervous System (CNS) problems
  • Meprobamate(Equanil, Meprospan 200, Meprospan 400, Probate, Apo-Meprobamate Highly addictive
  • Chlorpropamide(Diabinese, NovoPropamide, Apo-Chlorpropamide)Prolonged hypoglycemia-Low blood sugar
  • Meperidine(Demerol) Confusion,CNS problems
  • Pentazocine(Talwin, Talwin Nx)Confusion,Hallucinations
  • Trimethobenzamide(Tigan,Stemetic,Tebamide, Tribenzagan, Trimazide)Can effect motor control
  • Belladonna alkaloids(Donnatal,Barbidonna)Hallucinations,confusion
  • Dicylomine(Bentyl, Bentylol, Spasmoban, Formulex) Nausea,Hallucinations
  • Hyoscyamine(Levsin,Hyosol, A-Spas-S/L, Cystospaz, Levbid, Levsinex Timecaps, Symax SL) Arrhythmia,dizziness,blurred vision
  • Propantheline(Pro-Banthine)Arrhythmia,dizziness,blurred vision
  • Carisoprodol(Soma,Vanadom)Poorly tolerated,weakness
  • Chlorzoxazone(Parafon Forte DSC, Remular-S, Paraflex) Poorly tolerated,weakness
  • Cyclobenzaprine(Flexeril)Poorly tolerated,weakness
  • Metaxalone(Skelaxin)Poorly tolerated,weakness,sedation
  • Methocarbamol(Robaxin)Poorly tolerated,weakness,sedation
  • Amitriptyline(Elavil)Poorly tolerated,sedative effects unpleasant
  • Chlordiazepoxide(Librium)Strong sedation,Adverse CNS effects
  • Diazepam(Valium)Prolonged sedation,risk of falls
  • Doxepin(Sinequan)Poorly tolerated,sedative effects unpleasant
  • Indomethacin(Indocin)Adverse CNS effects
  • Dipyridamole(Persatine)Sudden blood pressure drop
  • Ticlopidine(Ticlid)Anti-clotting,more toxic than aspirin
  • Methyldopa(Aldomet,Aldoril)Low resting heart rate,exacerbate depression
  • Reserpine(Harmonyl, Serpasil, Serpalan, Novoreserpine) Depression,sedation, blood pressure drop
  • Dispyramide(Norpace, Norpace CR)Could induce heart failure,other complications
  • Oxybutynin(Ditropan,Ditropan XL,Oxytrol)Weakness, sedation, poor tolerance
  • Chlorpheniramine(Chlor-Trimeton,Aller-Chlor, Chlorate, Chlo-Amine)Increased heart rate,disorientation
  • Cyproheptadine(Periactin)Increased heart rate, disorientation
  • Diphenhydramine(Benadryl,Nytol)Increased heart rate, disorientation
  • Hydroxyzine(Vistaril,Rezine, Atarax)Increased heart rate, disorientation
  • Promethazine(Pheneragan, Promacot)Increased heart rate, disorientation
  • Propoxyphene(Darvon, Darvon-N)Highly addictive;avoid if depressed with suicidal thoughts.
UCLA Medical Center, Division of Geriatrics and Johns Hopkins Medical Letter, Health After 50
September 2008

Clostridium difficile, A Dangerous Superbug
There are probably very few of us who haven't been hospitalized at one time or another. Illnesses that you acquire during a stay in a hospital or longterm care facility are by no means new; however, in recent years, the infections have reached epidemic proportions in these institutions world wide. One of the most widespread and potentially serious of these illnesses is caused by the bacterium Clostridium difficile. This superbug is also known as Clostridium difficile Colitis, C.diff, C.difficile, Antibiotic Associated Colitis,CD, AACD and CDC.

C.difficile is a rising threat. Few Americans had heard of this intestinal bug until a study sponsored by the Association for Professionals in Infection Control and Epidemiology (APIC) showed the prevalence of C.Diff is 20 times higher than previous estimates. Findings suggest that on a average day, nearly 7,200 hospitalized patients - 13 of every 100- are colonized or, more often, infected with C.diff, and about 300 patients will not survive it.

C.difficile bacteria are everywhere in the environment. Three percent of healthy humans carrry it in the gut, but carriage rates in hospital patients tend to be much higher, and elderly persons being treated with antibiotics are most at risk of developing infections.This happens because the antibiotics administered kill the "friendly" gut flora and C.Diff flourishes as a result. In fact, Hospital infections kill 90,000 Americans a year. These bacteria produce spores when they encounter unfavorable conditions. Transmission of infection is through the ingestion of these spores which can survive on surfaces, floors and even clothing for years and, with the exception of chlorine bleach, are resistant to many disifectants and antiseptics, including alcohol hand gel. Do not conclude that C.difficile is confined exclusively to hospitals and similar institutions. It's also a growing problem among otherwise healthy people and the problem is growing worse. It is, according to the Centers for Disease Control, responsible for tens of thousands of cases of diarrhea.

Some people who are infected with C.difficile never become sick, though they can still spread the infection. Others have bouts of watery diarrhea with nausea and abdominal pain and cramping. And, an increasing number of persons develop severe inflammations of the colon. Complications of C.difficile infections include dehydration, kidney failure, bowel perforation, toxic megacolon and death. Signs and symptoms of this potentially life threatening illness include profuse, watery diarrhea 10 or more times a day, a fever, often greater than 101F, abdominal pain which may be severe, blood or pus in the stool, nausea, dehydration and weight loss.

Although more people with no known risk factors, including children, are contracting C.difficile infections, your risk is greatest if you:

    Are taking or recently have taken antibiotics, especially ampicillin, amoxicillin, clindamycin, fluoroquinolones and cephalosporins. Other antimicrobials, including antiviral and antifungal drugs, and chemotherapy medications also can lead to increased risk.

    Are 65 years of age or older. Older adults have a disproportionately high infection rate.

    Have a serious underlying illness or weakened immune system.

    Are or have recently been hospitalized, especially for an extended period. In general, larger hospitals have higher infection rates than do smaller hospitals.

    Live in a nursing home or longterm care facility. Often the infection spreads when patients are transferred from hospitals to other facilities.

    Have had abdominal surgery.

    Have a chronic colon disease such as inflammatory bowel disease or colorectal cancer.

    Take prescription or over-the-counter antacids. By reducing stomach acid, these drugs may allow C.difficile to pass more easily into the intestine.

    Have had a previous C.difficile infection.

Among the steps you can take to stop C.difficile from infecting you is to take antibiotics only when absolutely necessary and, even then, ask your Doctor to prescribe one that has a narrow range that you take for the shortest period of time so as to disrupt intestional bacteria the least. You my also consider Probiotic Supplements which help replace beneficial bacteria that antibiotics destroy. Only Saccharomyces boulardi has proved effective in C.difficile infections however. Last of all, the simplest and one of the best preventatives is to wash, wash, wash your hands! See Hand Washing 101 article on this same Health Alerts Page.

To learn more, Consumers Union offers information on states requiring hospitals to report infection rates. Go to www.stophospitalinfections.org/learn.html and click on "State Hospital Infection Disclosure Laws." Also, the Leapfrog Groups website www.leapfroggroup.org provides ratings of 1,300 U.S. hospitals and information on infection prevention measures. You can also Google the Centers for Medicare & Medicaid Services, at hospitalcompare.hhs.gov that reports quality information on hospitals. The Committee to Reduce Infection Deaths, at hospitalinfection.org. and finally, the Society for Healthcare Epidemiology of America. Go to shea-online.org and click on "Patient Guides."

Society for General Microbiology

Mayo Clinic

The Association for Professionals in Infection Control and Epidemiology


Calcium Supplements - How much REALLY?
Many people take calcium supplements to help stave off bone loss, but how much calcium you actually get from a supplement is not as straightforward as it may seem. In nature, calcium exists only as a compound (such as calcium carbonate or calcium citrate). Each compound contains a different amount of "elemental" calcium which is the important ingredient needed for bone health.

When you take a calcium supplement, it's the amount of elemental calcium that's the key to bone health. If the amount isn't clearly stated on the bottle, check the Nutrition Facts label, which will include how much elemental calcium - often listed simply as "calcium" - is in a serving size. The following example illustrates the point. Tums Ultra 1000 contains 1,000mg of calcium carbonate per tablet, BUT only 40% of the calcium carbonate is elemental calcium, meaning one tablet has only 400mg of the essential mineral needed.

Too many times the recommended serving size on the supplement label does not meet your daily calcium requirement. Again using the same simple example, Tums Ultra 1000 lists a serving size as two tablets, adding up to 800mg of calcium - not nearly enough for adults over the age of 50, who should get 1,200 to 1,500mg a day.

If you have questions about the correct dosage, ask your doctor or health care provider how many pills you should take per day. Also, it's best to spread out your daily dosage of calcium so you don't take more than 600mg of elemental calcium at one time; the body absorbs larger amounts less efficiently. Finally, take calcium carbonate with meals, because this type of calcium is absorbed better in the presence of stomach acid.

The Johns Hopkins Medical Letter

Heart Failure
The words "heart failure" certainly sound scary. If you've been told that you have heart failure or you're at risk, you may fear that your heart is about to quit working at any second! What heart failure really means is that your heart isn't working as well as it should. Your heart muscle has weakened, and it can't pump enough oxygen-rich blood to meet all of your body's needs. With proper treatment, many people with heart failure experience an improvement of symptoms and heart function and live relatively normal lives.

If you've been diagnosed with heart failure or have been told that you may be at risk, it's important that you work with your doctor to develop a treatment plan that addresses your needs and the severity of your disease. The two basic components of most treatment plans are medication and lifestyle changes.

The best way to respond to heart failure is to educate yourself, listen to your doctor's advice and pay attention to what your body is telling you.

Warning signs of heart failure tend to develop gradually. Because they come on slowly, in the disease's early stages, signs and symptoms may be missed or attributed to another condition. Here are some of the most common signs and symptoms of heart failure and some of what causes them.

Shortness of Breath- Because the heart can't pump blood fast enough, it "backs up" in the veins that connect the lungs to the heart causing fluid to leak into the lungs, producing shortness of breath, especially when lying down.

Cough or Wheezing-Similar to shortness of breath, the leaking fluid into the lungs produces a cough or wheeze.

Swelling of Body Tissues-When blood flow back to the heart slows, fluid builds up in tissues such as the lungs, feet, legs and abdomen. The kidneys also become less efficient in disposing of water and sodium. making tissues more susceptible to fluid retention.

Weight Gain- Fluid retention causes weight gain

Fatigue-With a reduced supply of freshly oxygenated blood to meet the body's needs, blood is diverted away from less vital organs, particularly muscles in the arms and legs, making them more susceptible to fatigue.

Reduced Appetite and Nausea-The digestive system receives less blood, thereby reducing appetite and causing digestive problems.

Difficulty Concentrating-Changes in blood components, such as an increase in sodium, can affect alertness, as can not getting enough blood to the brain.

Increased Heart Rate-To try to make up for its reduced capacity to pump blood, the heart beats faster.

Mayo Clinic Health Letter Special Report

Hand Washing 101
One of the things that you didn't learn in kindergarten and, in all probability, didn't learn from your Mom either is how to effectively wash your hands! That may sound silly to you but, in truth, the best defense against bacteria, even the dreaded superbugs like Methicillin-resistant Staphylococcus (MRSA) and Clostridium difficile (C.diff), is to keep your hands scrupulously clean. This is how you should do it:

Use warm water, not hot water and not cold water because hot water is hard on the hands and cold water will inhibit the sudsing of soap.

Next, you do not have to use expensive antibacterial soaps to try to kill the germs but you do need to work up a substantial lather of soap suds to dislodge the bacteria and suspend them in the suds.

While lathering your hands be sure to soap every millimeter of skin, including the thumbs, between the fingers, the backs of the hands and the undersides of the fingernails. Use a nail brush to be even more effective.

Now rinse your hands thoroughly with warm water to remove every last trace of soap suds (and germs).

Now that you have done such a great job, do not negate you efforts by grabbing the faucet tap (loaded with germs) or a door knob (especially in a public restroom). Instead use a paper towel to shut off the water and to open the door. That will go a long way in preserving the clealiness of your hands.

Last of all - teach a child how to wash his or her hands!



How Low Should You Go?
Aggressively treating high blood pressure may not be good medicine after age 80, according to a new study reported in the Journal of the American Geriatrics Society(Volume 55, page 383)

In this study, researchers looked at the medical records of more that 4,000 veterans age 80 and older with high blood pressure. Participants who lowered their blood pressure to just below the upper limit of normal - 139/89 mm Hg - were less likely to die of any cause over a five year period than those who reduced their blood pressure to lower levels. This relationship held when the researchers took into account other illnesses that can lead to premature death.

These findings do not contradict current guidelines that recommend lowering blood pressure to below 140/90 mm Hg. But they do suggest that aggressive lowering of blood presure beyond this level could be harmful for people over age 80, possibly because of reduced blood flow to vital organs.

If you are 80 or older and experience any symptoms of aggressive blood-pressure lowering such as dizziness, weakness, or thinking problems tell your doctor who then may make changes to your treatment regimen.

Johns Hopkins Health Alerts, Hypertension and Stroke
August 2008

Sleep Deprivation
When you are sleep deprived, cognition is one of the first functions to decline. Shortchange yourself on sleep by staying up late, continue this night after night, and you ultimately shortchange your memory. And if the problem is not resolved, your menory - and your brain - will not be functioning in the best way possible.

As people get older, a decrease begins in both the total time sleeping and the amount of time spent in the stage of sleep associated with dreaming. A newborn sleeps 16 hours per day. In contrast, the baby's 30-year-old mother sleeps six hours per day (if she's lucky), and only one quarter of this time ,or two hours, is occupied by the deepest stage of sleep.

Startine in middle age (between 46 and 60), not only does the amount of sleep per night start to decrease, but also the character of the sleep changes, People at these ages spend less time in the stage of sleep associated with dreaming and more time in the lighter stages.

As people get older, they are more likely to shift the time when they sleep, some going to bed and to sleep earlier and waking up earlier. Others are the opposite, staying up late into the night and sleeping much of the day. When people are in their 80s, these changes are even more pronounced. Their total time asleep per day may be only six or seven hours, including time spent in daytime naps. Even though a person may take several naps a day, the total time sleeping in naps is rarely over an hour. The idea that older individuals should sleep soundly for eight to ten hours is clearly wrong.

As a rule of thumb, one hour of sleep is required for two hours of being awake. As we get older, that ratio becomes closer to 45 minutes of sleep for each two hours awake. In other words, throughout the day you gradually accumulate a "sleep debt." By the end of a 16 hour day, a younger person owes the "sleep bank" eight hours. In contrast, an older person has a sleep debt of only about six hours. By the end of a week, you may have accumulated a sleep debt of 8 to 10 hours.

If you don't allow enough time for sleep, you become sleep deprived. Besides being sleepy during the daytime, sleep-deprived people often have problems with their thinking. They are slower to learn new things, they may have problems with their memory, and their ability to make judgements may be faulty, enough so that they may think they are starting to "lose it" when the real problem is not enough sleep.

Elderly people do not recover from sleep deprivation as quickly as younger people. In expermental situations where people are kept awake for 24 hours, those in their 70s take at least a day longer to recover from their subsequent daytime sleepiness than younger people. Gender may also make a difference in the time it takes to recover from sleep deprivation; women seem to be able to recover faster than men.

Johns Hopkins Memory Bulletin

Red Flag For Women
Contrary to typical portrayals in movies and on TV, heart attacks don't always have a sudden, intense onset. A recent study finds that for women, chronic chest pain may signal a future heart problem.

Although no one likes to think about having a heart attack,would you know what to do if you were? Even if you know what to do, would you follow through and more importantly, would you do it quickly?

According to the National Heart, Lung, and Blood Institute close to one million people in the United States have heart attacks each year; and, about one fifth of them die. Half of the deaths occur in the first hour after heart attack symptoms start and before the person reaches a hospital. These numbers underscore the importance of recognizing heart attack symptoms quickly and responding to these symptoms just as quickly,

Now a study in the European Heart Journal (Volume 27, page 1408) reports that for women, persistent chest pain may be a waning of future heart problems - even when a woman has no evidence of blockages in her coronary arteries.

The findings come from a study known as WISE, a government-funded project designed to evaluate chest pain in women - a task that is less straightforward than in men. The central isue is that women are much more likely than men to suffer long-term chest pain in the absence of any large artery blockages. But that doesn't mean their chest pain is innocuous.

Among women in the study with no signs of clogged arteries, those with persistent chest pain for at least a year were more that twice as likely to suffer a heart attack, stroke or other cardiovascular complication over the next five years. The study included 637 women whose chest pain and other potential symptoms of coronary heart disease were evaluated by angiography (an x-ray examination of blood vessls that can detect blockages).

The take home message is if you are a woman, you should not simply live with chronic chest pain if angiography fails to detect artery blockages. Instead, you should ask your doctor about ways you can reduce any heart risk factors you have. Remember, a healthy diet and regular physical activity are two of the most important ways.

Johns Hopkins Health Alerts

It Could Be A Warning of A Stroke
Recent research from the Journal Neurology explains why acting promptly at the first sign of a transient ischemic attack (TIA) may prevent a major stroke.

You probably know the symptoms of a heart attack, but it's just as important to know the symptoms of a stroke. Like a heart attack, a stroke is an emergency that requires immediate medical attention. Even a TIA, in which the stroke symptoms appear suddenly and quickly subside, is a medical emergency.

Whether you are having an ischemic or hemorrhagic stroke, the symptoms are the same. With a TIA,the symptoms are transitory, often lasting only minutes. If you or someone you are with experiences the sudden onset of any of the stroke symptoms listed below - even if the symptoms start to subside - you MUST call 911 or go straight to the hospital. Rapid diagnosis and treatment of a stroke may minimize damage to the brain tissue and improve the chances of survival. Stroke symptoms include:

Sudden weakness or numbness in the face, arm, or leg on one side of the body.
Sudden loss, blurring,or dimness of vision.
Mental confusion, loss of memory, or sudden loss of consciousness.
Slurred speech, loss of speech, or problems understanding others.
A sudden, severe headache with no apparent cause.
Unexplained dizziness, drowsiness, or lack of coordination.
Nausea and vomiting, especially when accompanied by any of the preceding symptoms.

The importance of responding immediately to symptoms of a stroke is underscored by a study in the journal Neurology(Volume 64, page 817). Note that the warning signs of an ischemic stroke may occur up to seven days before the event itself, according to researchers, and these signs should be taken seriously to minimize the chance of a major stroke.

Johns Hopkins Medicine

Detecting Delirium
Delerium may be difficult to detect, particularly in people with memory problems or dementia. Be sure to make allowances for certain personality traits - tell the doctor if a loved one is typically restless or introverted, for instance.

There is no universal rating system to help determine if a patient has delerium; however, the reliability of the following criteria tested positively in a study published in the Journal of Geriatric Psychology. Some central characteristics that researchers identified are listed below. Examples of the type of behavior that might indicate each characteristic are also included.

Shifting attention
Unable to concentrate during conversations.
Switches topics frequently.
Easily distracted.
Completely inattentive.

Poor orientation
Has problems articulating the date.
Doesn't know the days of the week.
Doesn't know where he or she is.
Has trouble recognizing family members.

Incoherence
Speech is difficult to understand.
Stops in the middle of a sentence.
Cannot express thoughts.

Restlessness and anxiety
Jumpy, edgy, or fidgety.
Suspicious of others.
Anxious and afraid.
Requires frequent reassurance.

Delusions and hallucinations
Perception is distorted or completely wrong.
Sees shapes or objects incorrectly.
Smells scents that are not there.

Poor cognition
Cannot spell simple words backwards.
Cannot do simple math.
Cannot recognize simple patterns of words or numbers.

Johns Hopkins Medical Letter

Viagra and Sleep Apnea
Sleep apnea is a disorder characterized by repeated episodes of breathing cessation (apnea) during sleep. These episodes last from 10 seconds to nearly a minute, ending with a brief partial arousal. Episodes of sleep apnea can occur and disrupt sleep hundreds of times throughout the night. An estimated 18 million Americans hve obstructive sleep apne, yet 95% of them are undiagnosed and untreated. Sleep apnea is about twice as common among men as among women.

A report in the Archives of Internal Medicine(9Volume 166, page 1763) suggests that taking Viagra at bedtime may worsen severe obstructive sleep apnea. This may be disturbing news to many men, because erectile dysfunction is particularily common among those with sleep apnea. Viagra prolongs the action of nitric oxide, which promotes upper airway congestion, thereby contributing to sleep apnea. The researchers studied 14 men with severe sleep apnea, who spent a night in a sleep lab having their breath and blood oxygen monitored after they took a single 50-mg dose of Viagra or a placebo.

Just one dose of Viagra significantly increased the amount of sleep time with a lower blood oxygen saturation level; while asleep, men who took Viagra were not getting as much oxygen as those wo took a placebo. They also had more breathing pauses per hour.

Bottom line advice on Viagra and sleep apnea is if you take Viagra and have sleep apnea, talk with your doctor about whether the pleasures you derive from taking the drug outweigh the risks of worsening your nighttime breathing problems.

A recent article from the Mayo Clinic Health Letter notes that neck circumference is one measurement that may be predictive of determining the risk of sleep apnea.The actual formula uses centimeters in its calculation, but approximate equivalents in inches are included here:

  • If you have or are treated for high blood pressure, add 4 cm (about 1 1/2 inches) to the neck measurement.
  • If you snore more than three nights a week, add an additional 3 cm (about 1 1/4 inches).
  • If you're known to choke or gasp most nights, add an additional 3 cm (about 1 1/4 inches).
If the final adjusted neck circumference is 43 cm (about 17 inches) to 48 cm (about 19 inches) your risk of sleep apnea is moderate. And if the adjusted measurement is more than 48 cm (about 19 inches) there's a high probability of sleep apnea. Talk to your doctor about whether you might have sleep apnea.

However, if your neck measurement is less than 43 cm (about 17 inches), but you have symptoms of sleep apnea, it's also important to speak with your doctor, as there may be some other treatable condition responsible for your symptoms.

Johns Hopkins Health Alerts

Mayo Clinic Health Letter


Gastroesophageal Reflux Disease (GERD)
Many people, including some 79% of those with gastroesophageal reflux disease suffer heartburn that awakens them during the night. While this is by far the most common symptom of GERD, there are about 10-15% of people with gastroesophageal disease who do NOT have heartburn! Instead, they experience asthma, a chronic cough, chest pain, or laryngitis. These symptoms result when stomach acid refluxes into organs connected to the esophagus, such as the larynx, trachea and lungs.

Research reported in the journal Chest (Volume 127, page 1658 May 2005) shows that people who are overweight, drink a lot of carbonated beverages, snore, experience daytime sleepiness or insomnia, have a high blood pressure or asthma, or use anti-anxiety medications such as diazepam (Valium) are most likely to experience the problem.

The subjects were part of the Sleep Heart Health Study, a national trial that enrolled 15,314 people to investigate the link between breathing problems during sleep and cardiovascular disease. Among the questions was "how often in the past year, on average, have you been awakened during the night with heartburn or indigestion?" The responses indicated that 1/4 or 3,806 people, in this group reported the symptom at least twice a month. People with nighttime heartburn are at greater risk for more serious esophageal problems such as erosive esophagitis, Barrett's esophagus, and esophageal cancer.

With both obesity and GERD on the rise , medical researchers have found there to be a link between the two. An article in The American Journal of Gastroenterology examined the results of 20 studies involving more than 18,000 people with GERD. Overall, people who were overweight were 50% more likely to have GERD than normal weight people; obese individuals were more than twice as likely.

If you experience nighttime heartburn on a regular basis, or have bouts of asthma, a nagging cough or episodes of chest pain, talk with your doctor. In addition, try to control the risk factors identified in this study - for example, keep your weight and blood pressure under control and cut down on your soda intake.

Johns Hopkins Medicine and Johns Hopkins Health Alerts

Distinguishing Normal "Senior Moments"
Concerned about memory? Johns Hopkins doctors compare symptoms of normal aging with those of more serious dementia.

Occasional memory lapses, such as forgetting why you walked into a room or having difficulty recalling a person's name, become more common as we approach our 50s and 60s. It's comforting to know that this minor forgetfulness is a normal sign of aging, not a sign of dementia.

Here are examples of the types of memory problems common in normal age-related forgetfulness, mild cognitive impairment and dementia.

Normal Age-Related Forgetfulness:

Sometimes misplaces keys, eyeglasses, or other items.
Momentarily forgets an acquaintances's name.
Occasionally has to "search" for a word.
Occasionally forgets to run an errand.
May forget an event from the distant past.
When driving, may momentarily forget where to turn. Quickly orients self.
Jokes about memory loss.

Mild Cognitive Impairment:

Frequently misplaces items.
Frequently forgets people's names and is slow to recall.
Finding the desired word becomes more difficult.
Begins to forget important events and appointments.
May forget more recent events or newly learned information.
May temporarily become lost more often.
May have trouble understanding and following a map.
Worries about memory loss. Family and friends notice the lapses.

Dementia:

Forgets what an item is used for or puts it in an inappropriate place.
May not remember having known a person.
Begins to lose language skills. May withdraw from social interaction.
Loses sense of time. Doesn't know what day it is.
Short-term memory is seriously impaired. Has difficulty learning and remembering new information.
May have little or no awareness of cognitive problems.

Johns Hopkins Health Alerts

Sleep and your Blood Pressure
Another reason to catch your Z's has to do with healthier blood pressure. In 90-95% of people with high blood pressure, doctors are unable to pinpoint the exact cause. In these cases, the condition is called essential or primary hypertension, In the remaining 5-10% of people, doctors are able to identifly a cause, and this type of high blood pressure is called secondary hypertension.

Now researchers may have found a connection between sleep habits and high blood pressure. In a study reported in the Journal Hypertension(Volume 47, page 833) researchers studied more than 4,800 Americans and found that young and middle-aged adults who clocked five or fewer hours of sleep each night were 60% more likely than their well-rested peers to develop hypertension over the next decade. Lack of sleep did not appear to raise blood pressure in adults older than age 59, however.

The link between sleep habits and blood pressure remained even agter the researchers controlled for weght, depression, smoking, and physical activity levels. This means there may be something about chronic sleep deprivation that raises a person's blood pressure.

One possibility us that people who get little sleep have more exposure to the elevations in heart rate, blood pressure, and nervous system activity that come with being awake. As a result, the body may adapt to these chronic elevations by operating at anew, higher level. Chronic sleep deprivation might also throw a wrench in the central "clock" in your brain, which governs the rythem of bodily processes, including blood pressure control. People vary in the amount of sleep they need, but experts recommend that adults get at least a good six hours of sleep a night.

John Hopkins Health Alerts

Primer on Cataracts
If you're in your forties or fifties, you probably know someone who has cataracts. That's because cataracts can occur at any age (in fact, babies can be born with them), they are most common later in life. About 50% of people age 65-74 and 70% of those age 75 and older have cataracts. In 2004, an estimated 20.5 million Americans over age 40 (approximately 17%) had a cataract. Cataract surgery is the most commonly performed surgical procedure in the United States. More than 1.5 million cataract operations are performed each year.

The cause of most cataracts is unknown, but at least two factors associated with aging contribute to their development. First, clumping of proteins in the lens leads to scattering of light and a decrease in the transparency of the lens. Second, the breakdown of lens proteins leads to the accumulation of a yellow-brown pigment that clouds the lens.

Researchers have found certain chemical changes in the eyes of people with cataracts. These changes include a reduced uptake of oxygen by the lens and a rise in the water content of the lens, which is later followed by dehydration. When cataracts form, levels of calcium and sodium in the lens increase, and levels of potassium, vitamin C, and protein decrease. In addition, lenses with cataracts appear to be deficient in the antioxidant glutathione; however, studies on the use of medications or vitamins to alter the levels of these substances in the lens have not produced promising results. Currently, there is no effective drug therapy to prevent cataracts from forming. But cigarette smoking, certain drugs, eye injuries, sunlight, diabetes and even obesity can increase the risk of cataracts.

Cataracts are an opacification (cloudiness) of the eye's normally clear crystalline lens and they form painlessly. The most common symptom is cloudy or blurry vision and everything becomes dimmer, as if seen through glasses that need cleaning. Most often, both eyes are affected, though vision is usually worse in one eye than in the other. Other symptoms include glare, halos, poor night vision, a perception that colors are faded or that objects are yellowish, and the need for brighter light when reading. Symptoms can develop rapidly (in a matter of months) or almost imperceptibly over many years.

Johns Hopkins Medicine

Antidepressant-Induced Sexual Dysfunction
Karen L. Schwartz, M.D., Director of Clinical Programs at the Johns Hopkins Mood Disorders Center weighs in on this all too common cause of decreased libido. Unfortunately, sexual dysfunction includes diminished libido, inability to orgasm, decreased sensation in the genitals, vaginal dryness, and erectile dysfunction.

If you report sexual dysfunction, the first thing your doctor will do is a thorough medical workup to rule out such physical problems as hypertension, diabetes, urological problems and neurological problems, all of which can cause such dysfunction.

If antidepressants are the likely cause, there are several possible remedies. First, you and your doctor may consider switching to an antidepressant with a low rate of sexual side effects, such as Wellbutrin (bupropion). This would be done carefully to minimize the risk of a relapse of depression. Your doctor may also suggest adding Wellbutrin to your current antidepressant regimen. Research has shown that small doses of Wellbutrin in combination with other antidepressants can be helpful in alleviating the sexual side effects of those antidepressants. There are a number of other remedies that you and your doctor might try such as adding sildenafil which is effective for combating antidepressant-induced sexual dysfunction in both men and women. Perhaps your doctor may decrease your antidepressant dose to some slight degree or change the time you take your medication. Dividing the medication dose and taking it twice a day may also diminish side effects. Finally, your doctor may have you take a "drug holiday" for a two day period which will lower the rate of sexual side effects without increasing the risk of a recurrence of depressive symptoms.

All remedies discussed above should be implemented only with physician support and supervision to prevent relapse of depressive symptoms and drug withdrawl reactions.

Depression and Anxiety

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